The Charcot’s disease that has just taken the astrophysicist Stephen Hawking touches 2,500 people each year in USA. This pathology is incurable, but its support in reference centers helps to slow down its evolution.
Here we write 5 points to know about Charcot’s Disease
- It is a rare disease
- ALS is due to degeneration of motor neurons
- The first symptom is the loss of muscle strength
- Its evolution is difficult to predict
- Treatment slows down the disease
HERE WE EXPLAIN THE REST OF ARTICLE
1- It is a rare disease
Charcot’s disease or amyotrophic lateral sclerosis (ALS) affects between 5,000 and 7,000 people currently in USA. Every year 2,500 new ones are diagnosed. The first signs appear on average around 60 years old. Continue reading: TIPS FOR TAKING CARE OF YOUR HANDS: HOW TO AVOID CHRONIC INJURIES AND PAIN
2- ALS is due to degeneration of motor neurons
By an unknown mechanism, the neurons responsible for sending the movement orders to the muscles gradually die. Over time, the patient loses the use of his legs and arms. Difficulty breathing, swallowing and talking are settling down.
The origin of the disease is not identified. In recent years, scientific studies have linked the occurrence of ALS with exposure to pesticides or diesel particles. Most of the time, the disease strikes in isolation. But there is a family form (due to genetic mutations). It represents less than 10% of cases.
3- The first symptom is the loss of muscle strength
In general, the disease is manifested by muscle weakness in the limbs, with cramps, painful contractures, and stiffness. An examination, the electroneuromyogram, makes it possible to evaluate the functioning of nerves and muscles.
4- Its evolution is difficult to predict
The disability is irreversible, but its evolution varies greatly from person to person. The disease can even stabilize in rare cases. Nevertheless, the outcome remains fatal in the more or less long-term.
5- Treatment slows down the disease
Riluzole, a DMARD, should be given at the onset of the disease. It reduces the level of glutamate present in excess in the nerve cells of patients. At the same time, physiotherapy, speech therapy, and occupational therapy sessions help the person to maintain their independence as long as possible. Psychological monitoring is essential, given the severity of the prognosis.
A National Diagnostic and Care Protocol (PNDS) has been drawn up by the High Health Authority. It is reviewed every four years and the last date of 2015. This PNDS is implemented in the 19 centers of recourse and competency SLA distributed throughout the territory.
Lifecell recommended to you read this article: Inflammation: So many causes, only one mechanism